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CURRENT PROJECTS

Learn about the work currently being conducted in

the laboratory! 

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The SHARE Study

The purpose of the SHARE (Sex Hormones, Alcohol, and Reward in Exposure to trauma) study is to learn more about the relationship between alcohol use and posttraumatic stress disorder (PTSD) symptoms. You are being asked to join because you are between 18 and 65 years old, are not currently taking hormone contraceptives (i.e., the birth control pill, injections, implants, intrauterine devices [IUDs], vaginal rings, and skin patches), have experienced at least one stressful life event, and have consumed alcohol within the last 30 days. We plan to enroll 120 participants in this study over 3 years.

PARTICIPATE IN THE SHARE STUDY

METHODS

Learn more about the technologies and methodologies we use in our studies.

MRI

 MRI 

Magnetic Resonance Imaging (MRI) uses a large magnet to take detailed internal pictures of the body and brain. By looking at the magnetic properties of blood in the brain, functional MRI (fMRI) can be used to observe brain activity. 

Selected Publications

  • Hinojosa, C.A., George, G.C, & Ben-Zion, Z. (2024). Hinojosa, C. A., George, G. C., & Ben-Zion, Z. (2024). Neuroimaging of posttraumatic stress disorder in adults and youth: progress over the last decade on three leading questions of the field. Molecular psychiatry, 10.1038/s41380-024-02558-w. Advanced online publication. doi: 10.1038/s41380-024-02558-w

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  • Hinojosa, C.A., VanElzakker, M.B., Kaur, N., Felicione, J.M., Charney, M.E., Bui, E., Marques, L., Summergrad, P., Rauch, S.L., Simon, N.M., & Shin, L.M. (2023). Pre-treatment amygdala activation and habituation predict symptom change in posttraumatic stress disorder. Frontiers in Behavioral Neuroscience, 17, 1198244. doi: 10.3389/fnbeh.2023.1198244

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  • Hinojosa, C. A., Liew, A., An, X., Stevens, J. S., Basu, A., van Rooij, S. J. H., House, S. L., Beaudoin, F. L., Zeng, D., Neylan, T. C., Clifford, G. D., Jovanovic, T., Linnstaedt, S.D., Germine, L. T., Rauch, S. L., Haran, J. P., Storrow, A. B., Lewandowski, C., Musey, P. I., Hendry, P. L., Sheikh, S., Jones, C. W., Punches, B. E., Kurz, M. C., Swor, R. A., Hudak, L. A., Pascual, J. L., Seamon, M. J., Datner, E. M., Chang, A. M., Pearson, C., Peak, D. A., Merchant, R .C., Domeier, R. M., Rathlev, N. K., Sergot, P., Sanchez, L. D., Bruce, S. E., Miller, M. W., Pietrzak, R. H., Joormann, J., Pizzagalli, D. A., Sheridan, J. F., Harte, S. E., Elliott, J. M., Kessler, R. C., Koenen, K. C., McLean, S. A., Ressler, K. J., & Fani, N. (2023). Associations of alcohol and cannabis use with change in posttraumatic stress disorder and depression symptoms over time in recently trauma-exposed individuals. Psychological Medicine, 1–12. doi: 10.1017/S0033291723001642

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  • Hinojosa, C.A., VanElzakker, M.B., Hughes, K.C., Offringa, R., Sangermano, L.M., Spaulding, I.G., Staples-Bradley, L.K., Whitman, E.T., Lasko, N.B., Rauch, S.L., Orr, S.P., Pitman, R.K., & Shin, L.M. (2022). Exaggerated amygdala activation to ambiguous facial expressions is a familial vulnerability factor for posttraumatic stress disorder. Journal of Psychiatric Research, 156, 451-459. doi: 10.1016/j.jpsychires.2022.10.049

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  • Hinojosa, C.A. (2022). Does hippocampal volume in patients with posttraumatic stress disorder vary by trauma type? Harvard Review of Psychiatry, 30(2), 118-134. doi: 10.1097/HRP. 0000000000000328

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